Is your turtle sense tingling? Is your bird brain humming? Your magneto sensitivity just may be working.
Research published in Nature Communications this week by faculty at the University of Massachusetts Medical School shows that a protein expressed in the human retina can sense magnetic fields when implanted into Drosophila, reopening an area of sensory biology in humans for further exploration.
Magnetic declination from true north in 2000.
Credit: Wikipedia
In many migratory animals, the light-sensitive chemical reactions involving the flavoprotein cryptochrome (CRY) are thought to play an important role in the ability to sense the Earth's magnetic field. In the case of Drosophila, previous studies from the Reppert laboratory (http://reppertlab.org/) have shown that the cryptochrome protein found in these flies can function as a light-dependent magnetic sensor.
In many migratory animals, the light-sensitive chemical reactions involving the flavoprotein cryptochrome (CRY) are thought to play an important role in the ability to sense the Earth's magnetic field. In the case of Drosophila, previous studies from the Reppert laboratory (http://reppertlab.org/) have shown that the cryptochrome protein found in these flies can function as a light-dependent magnetic sensor.
Magnetic Field of Earth
Credit: Wikipedia
To test whether the human cryptochrome 2 protein (hCRY2) has a similar magnetic sensory ability, Steven Reppert, MD, the Higgins Family Professor of Neuroscience and chair and professor of neurobiology, graduate student Lauren Foley, and Robert Gegear, PhD, a post doctoral fellow in the Reppert lab now an assistant professor of biology and biotechnology at Worcester Polytechnic Institute, created a transgenic Drosophila model lacking its native cryptochrome protein but expressing hCRY2 instead. Using a behavioral system Reppert's group previously developed, they showed that these transgenic flies were able to sense and respond to an electric-coil-generated magnetic field and do so in a light-dependent manner.
These findings demonstrate that hCRY2 has the molecular capability to function in a magnetic sensing system and may pave the way for further investigation into human magnetoreception.
To test whether the human cryptochrome 2 protein (hCRY2) has a similar magnetic sensory ability, Steven Reppert, MD, the Higgins Family Professor of Neuroscience and chair and professor of neurobiology, graduate student Lauren Foley, and Robert Gegear, PhD, a post doctoral fellow in the Reppert lab now an assistant professor of biology and biotechnology at Worcester Polytechnic Institute, created a transgenic Drosophila model lacking its native cryptochrome protein but expressing hCRY2 instead. Using a behavioral system Reppert's group previously developed, they showed that these transgenic flies were able to sense and respond to an electric-coil-generated magnetic field and do so in a light-dependent manner.
These findings demonstrate that hCRY2 has the molecular capability to function in a magnetic sensing system and may pave the way for further investigation into human magnetoreception.
Credit: Wikipedia
"Additional research on magneto sensitivity in humans at the behavioral level, with particular emphasis on the influence of magnetic field on visual function, rather than non-visual navigation, would be informative," wrote Reppert and his colleagues in the study.
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